Method for Producing Compositions Containing Glucosylceramide
Product name
Fermented Rice Germ Extract
Title of invention
Method for producing compositions containing glucosylceramide
Patent number
6579619
Date of filing
October 2, 2015
Date of grant
September 6, 2019
Summary
Problem to be solved: To provide a simple method for producing compositions containing a high concentration of glucosylceramide.
Solution:
(1) A method for producing a composition containing glucosylceramide comprising the following steps: fermenting rice bran and/or rice germ to obtain a fermented product; extracting the fermented product with a polar solvent to obtain an extract of the fermented product; and then partitioning the extract.
(2) A method for producing compositions containing glucosylceramide described in (1) above, wherein the rice bran and/or rice germ is a defatted one.
(3) A method for producing compositions containing glucosylceramide described in (1) or (2) above, wherein the partition is a liquid-liquid partition with hexane and water; the resulting aqueous layer is then partitioned with ethyl acetate and water; the resulting aqueous layer is then partitioned with chloroform and methanol; and then the chloroform layer is separated.
(4) A method for producing compositions containing glucosylceramide described in any one of (1) to (3) above, wherein the fermented product is obtained through fermentation with Aspergillus oryzae.
Method for Producing Compositions Containing Stigmasterol
Product name
Fermented Rice Germ Extract
Title of invention
Method for producing compositions containing stigmasterol
Patent number
6584899
Date of filing
October 2, 2015
Date of grant
September 13, 2019
Summary
Problem to be solved: To provide a simple method for producing compositions containing a high concentration of stigmasterol.
Solution:
(1) A method for producing a composition containing stigmasterol comprising the following steps: fermenting rice bran and/or rice germ to obtain a fermented product; extracting the fermented product with a polar solvent to obtain an extract of the fermented product; and then partitioning the extract.
(2) A method for producing compositions containing stigmasterol described in (1) above, wherein the rice bran and/or rice germ is a defatted one.
(3) A method for producing compositions containing stigmasterol described in (1) or (2) above, wherein the partition is a liquid-liquid partition with hexane and water, and then the hexane layer is separated off.
(4) A method for producing compositions containing stigmasterol described in any one of (1) to (3) above, wherein the fermented product is obtained through fermentation with Aspergillus oryzae.
Method for Producing Compositions Containing β-sitosterol Glucoside
Product name
Fermented Rice Germ Extract
Title of invention
Method for producing compositions containing β-sitosterol glucoside
Patent number
6604806
Date of filing
October 2, 2015
Date of grant
October 25, 2019
Summary
Problem to be solved: To provide a simple method for producing compositions containing a high concentration of β-sitosterol glucoside.
Solution: A method for producing compositions containing β-sitosterol glucoside represented in chemical formula (1) comprising the following steps: fermenting defatted rice bran and/or rice germ using Aspergillus oryzae to obtain a fermented product; extracting the fermented product with a polar solvent to obtain an extract of the fermented product; partitioning the extract with hexane and water; partitioning the resulting aqueous layer with ethyl acetate and water; further partitioning the resulting aqueous layer with a mixture of chloroform and methanol; and then separating the chloroform-methanol mixed layer.
Method for Producing Compositions Containing Ergosterol Peroxide
Product name
Fermented Rice Germ Extract
Title of invention
Method for producing compositions containing ergosterol peroxide
Patent number
6645791
Date of filing
October 2, 2015
Date of grant
January 14, 2020
Summary
Problem to be solved: To provide a simple method for producing compositions containing a high concentration of ergosterol peroxide.
Solution:
(1) A method for producing a composition containing ergosterol peroxide comprising the following steps: fermenting rice bran and/or rice germ to obtain a fermented product; extracting the fermented product with a polar solvent to obtain an extract of the fermented product; and then partitioning the extract.
(2) A method for producing compositions containing ergosterol peroxide described in (1) above, wherein the rice bran and/or rice germ is a defatted one.
(3) A method for producing compositions containing ergosterol peroxide described in (1) or (2) above, wherein the polar solvent used to partition the liquid is chloroform and methanol.
(4) A method for producing compositions containing ergosterol peroxide described in any one of (1) to (3) above, wherein the fermented product is obtained through fermentation with Aspergillus oryzae.
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