Problem to be solved: To provide a novel AMPK activator.
Solution:
(1) An AMPK activator containing black ginger extract as an active component.
(2) An AMPK activator containing a polymethoxyflavone as an active component.
(3) An AMPK activator wherein the polymethoxyflavone described in (2) above is 5,7-dimethoxyflavone.
Energy Metabolism Activator for Muscle Cells
Product name
Black Ginger Extract
Title of invention
Energy Metabolism Activator for Muscle Cells
Patent number
6751709
Date of filing
March 24, 2016
Date of grant
August 19, 2020
Summary
"The invention provides a novel energy metabolism activator for muscle cells along with a composition that can be ingested as a medical and pharmaceutical products or food. The technical features of the invention designed to solve the above problem are as follows:
(1) A glucose transporter (GLUT4) gene expression promoter containing, as an active component, at least one compound selected from among 5-hydroxy-3,7-dimethoxyflavone, techtochrysin, 3,7,4'-trimethyl kaempferol, retusine, pentamethyl quercetin, trimethyl apigenin, tetramethyl kaempferol, and 5,7-dimethoxyflavone.
(2) A glucose transporter (GLUT4) gene expression promoter containing at least one from techtochrysin and 5,7-dimethoxyflavone as an active component.
(3) A glucose transporter (GLUT4) gene expression promoter for muscle cells containing any one of the compounds represented by chemical formula (1) below [wherein R1 and R2 represent hydrogen and an alkyl group containing 1 to 3 carbon atoms]."
ＴＮＦ－α及びＩＬ－６産生抑制剤及びそれを用いた筋肉炎症抑制剤
Product name
Black Ginger Extract
Title of invention
TNF-α and IL-6 production inhibitor and muscle inflammation inhibitor using same
Patent number
6954960
Date of filing
August 5, 2015
Date of grant
June 19, 2023
Summary
Problem to solve: To provide a novel inhibitor of gene expression of TNF-α and IL-6 caused by exercise-induced skeletal muscle damage.
Solution:
(1) A TNF-α gene expression inhibitor and activator containing black ginger extract as an active ingredient.
(2) An IL-6 gene expression inhibitor containing black ginger extract as an active ingredient.
(3) An inhibitor of muscle inflammation caused by exercise-induced skeletal muscle damage containing the agent of (1) or (2) above as an active ingredient.
(4) An agent for improving muscle pain containing any one of the agents of (1) to (3) above as an active ingredient.
(5) An agent for improving muscle fatigue containing any one of the agents of (1) to (3) above as an active ingredient.
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