オリザ油化株式会社

Research and Development

Patents

Estrogen Activity Regulator and Application Thereof as Ameliorative Agent for General Malaise

Product name
Aguaje Extract
Title of invention
Estrogen activity regulator and application thereof as ameliorative agent for general malaise
Patent number
6742537
Date of filing
April 23, 2019
Date of grant
July 30, 2020
Summary
Problem to be solved: To provide an estrogen activity regulator containing a novel active component that exhibits estrogenic effects in the absence of estrogen and acts antagonistically in the presence of estrogen; and an application thereof as an ameliorative agent for general malaise related to the menstrual cycle. Solution: The features of the invention designed to solve the above problem are as follows: (1) An estrogen activity regulator that exhibits estrogenic effects in the absence of estrogen and estrogen-inhibiting effects in the presence of estrogen, which contains a pterocarpan compound as an active component. (2) An estrogen activity regulator that exhibits estrogenic effects in the absence of estrogen and estrogen-inhibiting effects in the presence of estrogen, which uses, as an active component, aguaje extract containing 8-hydroxyhomopterocarpan and lespeflorin G8. (3) An ameliorative agent for general malaise accompanying the menstrual cycle, which contains a pterocarpan compound as an active component. (4) An ameliorative agent for general malaise accompanying the menstrual cycle, which uses, as an active component, aguaje extract containing 8-hydroxyhomopterocarpan and lespeflorin G8.
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